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Association of Helicobacter pylori Infection With Psoriasis and Lichen Planus: Prevalence and Effect of Eradication Therapy
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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Recently a debate about the association between Helicobacter pylori (HP) and various dermatologic conditions has been reported.1-3 We designed a case-control study of a population-based sample to assess the prevalence of HP infection and the effects of bacterium eradication on the outcome of the cutaneous lesions in patients affected by psoriasis and lichen planus.
Subjects and Methods
A total of 145 patients (75 men, 70 women; mean age, 44.7 years), 84 with psoriasis and 61 with lichen planus, were included. The control patients were taken from a census-based randomized sample from the same geographic area. Helicobacter pylori infection was examined with the carbon 13 urea breath test (UBT). Eradication therapy included treatment with oral omeprazole, amoxicillin, and clarithromycin for 1 week. Clinical response was evaluated for at least 1 year from eradication.
Results
Data on frequency of positive findings and titer in patients with psoriasis and with lichen planus vs controls are summarized in . . . [Full Text of this Article] Comment
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