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Generalized Erythematous Plaques
Boo-Peng Khoo, MD;
Yong-Kwong Tay, MD;
Suat-Hoon Tan, MD
National Skin Centre, Singapore
Arch Dermatol. 2000;136:665-670.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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REPORT OF A CASE
A 27-year-old Chinese man presented with a nonpruritic rash on his thumbs that had developed gradually over a 1.5-year period (Figure 1). Similar lesions subsequently appeared on the antecubital fossae, knees (Figure 2), and popliteal fossae. The lesions were persistent and nonmigratory and were apparently aggravated by heat and sweating. The patient had a younger brother, who was similarly affected. His medical history was otherwise unremarkable.
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Figure 1.
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Figure 2.
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On physical examination, well-demarcated, symmetric, lichenified, erythematous plaques were noted over the dorsa of both hands, the antecubital fossae, the knees, and the popliteal fossae. The palms and soles were unaffected. A punch skin biopsy specimen was obtained from the dorsum of the left hand (Figure 3).
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Figure 3.
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What is your diagnosis?
Diagnosis: Progressive symmetric erythrokeratodermia (PSEK) (erythrokeratodermia progressiva symmetrica).
Microscopic examination of the punch biopsy specimen revealed orthokeratotic hyperkeratosis and slight . . . [Full Text of this Article]
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