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We read with great interest the article by Ruzicka et al¹ on the possible role of human herpesvirus (HHV) 6 in the etiology of papular-purpuric gloves-and-socks syndrome (PPGSS). This is a newly recognized dermatosis. Nearly 30 cases have been described in the European literature¹ and already 2 documented cases in the United States.² As possible causative agents, either human parvovirus (HPV) B19 (in half of the cases)^2-4 or measles virus, cytomegalovirus, Coxsackievirus B6, hepatitis B virus,⁵ or no viral cause has been reported in individual cases based on serological evidence.

Report of a Case

Our patient was a 13-year-old girl in good general condition. Four days prior to hospitalization, erythematous lesions appeared and became confluent on her hands and feet, accompanied by swelling, pruritus, and pain. Similar lesions developed in the axillary and inguinal regions. She experienced high fever. Abdominal ultrasonogram and chest radiograph results showed no pathologic findings. Next, her hands and feet . . . [Full Text of this Article]

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