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  Vol. 136 No. 6, June 2000 TABLE OF CONTENTS
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  The Cutting Edge: Challenges in Medical and Surgical Therapeutics
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Regression of Deeply Infiltrating Giant Condyloma (Buschke-Löwenstein Tumor) Following Long-term Intralesional Interferon Alfa Therapy

Alexandra Geusau, MD; Gertraud Heinz-Peer, MD; Beatrix Volc-Platzer, MD; Georg Stingl, MD; Reinhard Kirnbauer, MD
From the University of Vienna Medical School, Vienna, Austria.

Arch Dermatol. 2000;136:707-710.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF A CASE

In 1995, a 40-year-old heterosexual man developed a perianal tumor that rapidly increased in size. Following a clinical and histologic diagnosis of a large condyloma acuminatum (CA), the tumor was partially resected in a primary care hospital. Subsequently, recurrent perianal fistulae and abscesses required several surgical interventions, and the patient underwent a transverse colostomy to allow subsequent complete resection of the condyloma.

At the patient's first visit in our clinic in 1996, physical examination demonstrated a smooth, exophytic, cauliflowerlike perianal verrucous tumor extending toward the perineum, scrotum, and buttocks (Figure 1, left). A magnetic resonance imaging scan revealed that the tumor infiltrated deeply into the right side of the pelvis, including the ischiorectal fossa, internal obturator muscle, anal sphincter, perineum, and penile root (Figure 2, top). Histologic reevaluation of a previously . . . [Full Text of this Article]

THERAPEUTIC CHALLENGE

SOLUTION

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