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Arch Dermatol. 2000;136:772-773.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The Effect of Nitrazepam on Nocturnal Scratching in Adults With Atopic Dermatitis: A Double-Blind Placebo-Controlled Crossover Study
Ebata T, Izumi H, Aizawa H, Kamide R, Niimura M
Br J Dermatol. 1998;138:631-634

Sedative antihistamines and benzodiazepines are often prescribed to patients with atopic dermatitis (AD) to reduce nocturnal itching and scratching, but their effects have been poorly studied. The objective of this double-blind, placebo-controlled, crossover trial was to assess the effect of nitrazepam on nocturnal scratching of 10 adult patients with AD by means of both objective and subjective outcome measures.

The patients, who were young adults with moderate to severe AD and remained stable for at least 6 months, continued to receive their usual topical treatment and oral antihistamine for more than a month before the study and for the 2 weeks of the study. They were randomized to receive nitrazepam or placebo on 3 consecutive nights in the . . . [Full Text of this Article]

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