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Questions Answered and a $1 Million Question Raised Concerning Lupus Erythematosus Tumidus
Is Routine Laboratory Surveillance Testing During Treatment With Hydroxychloroquine for Skin Disease Really Necessary?
Richard D. Sontheimer, MD
Arch Dermatol. 2000;136:1044-1049.
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INTRODUCTION
After a professional lifetime of studying the cutaneous manifestations of lupus erythematosus (LE), I have found LE tumidus (LET) (also referred to, perhaps incorrectly, as lupus tumidus and tumid LE by modern dermatologists) to be the most enigmatic form of cutaneous LE (CLE). The clinical and pathogenetic significance of LET has until very recently been ignored completely in the medical literature published in English. While preparing comprehensive reviews of LE-specific skin disease in the past,1 virtually no published literature on this form of CLE in English could be found in the MEDLINE database. When performing a text word search of the term lupus tumidus in MEDLINE, one comes up as often with case descriptions of cutaneous tuberculosis2 as CLE. However, Kuhn and coworkers3 from the Department of Dermatology at Heinrich-Heine-University in Düsseldorf, Germany, have begun to illuminate the nature and significance of this form of CLE . . . [Full Text of this Article]
A MODERN VIEW OF LET
THREE CHEERS FOR OUR INTERNATIONAL COLLEAGUES IN MEDICAL DERMATOLOGY
LAGNIAPPE
Is There a Need for Routine Laboratory Surveillance During Treatment With Hydroxychloroquine and Other Aminoquinoline Antimalarials? The Need for a Multicenter Mechanism to Promote Systematic Patient-Oriented Research in Orphan Dermatological Diseases
From the Department of Dermatology, The University of Iowa College of Medicine/The University of Iowa Health Care, Iowa City.
RELATED ARTICLE
Lupus Erythematosus Tumidus: A Neglected Subset of Cutaneous Lupus Erythematosus: Report of 40 Cases
Annegret Kuhn, Dagmar Richter-Hintz, Claudia Oslislo, Thomas Ruzicka, Mosaad Megahed, and Percy Lehmann
Arch Dermatol. 2000;136(8):1033-1041.
ABSTRACT
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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
LET Us Remember
Journal Watch Dermatology 2000;2000:6-6.
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