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Widespread Pea-Sized Papules and Gooseflesh Plaques in a 44-Year-Old Woman
John G. Albertini, MD;
Michele Maroon, MD;
William B. Tyler, MD
Geisinger Medical Center, Danville, Pa
Arch Dermatol. 2000;136:1055-1060.
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REPORT OF A CASE
A 44-year-old white woman presented with numerous asymptomatic 5- to 10-mm flesh-colored, firm papules on her hands, wrists (Figure 1), back, and shoulders that she had had for many years. Examination revealed gooseflesh plaques in both antecubital fossae and on the lateral aspect of her neck. A punch biopsy specimen from the antecubital fossa was stained with hematoxylin-eosin (Figure 2) and elastin (Figure 3). A radiograph of her pelvis was obtained (Figure 4).
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Figure 1.
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Figure 2.
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Figure 3.
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Figure 4.
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What is your diagnosis?
Diagnosis: Buschke-Ollendorff syndrome.
On scanning magnification, the biopsy specimen appeared normal. Higher magnification showed clusters of smaller collagen bundles that were irregularly arranged. The elastin stain showed increased elastic fibers in the areas of altered collagen; the elastic fibers were coarse, irregular, and interconnected. These findings are characteristic of . . . [Full Text of this Article]
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