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  Vol. 136 No. 8, August 2000 TABLE OF CONTENTS
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Long-term Efficacy of Tacrolimus Ointment for Recalcitrant Facial Erythema Resistant to Topical Corticosteroids in Adult Patients With Atopic Dermatitis

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Recalcitrant facial erythema often occurs in adults with atopic dermatitis and resists common therapies, including topical corticosteroids.1 Recently, several authors have reported that short-term use of tacrolimus (FK506) ointment, a newly developed immunosuppressant drug, shows excellent results with recalcitrant facial erythema.2-5 In the present study, we analyzed the effects of long-term applications of topical tacrolimus on red face conditions.

Patients and Methods

After obtaining informed consent, 51 adult patients (age range,16-44 years) with atopic dermatitis, who had steroid-resistant diffuse indurated erythema on the face for 1 to 23 years (average, 5 years), were included in the study. All fulfilled Hanifin and Rajka's diagnostic criteria6 for atopic dermatitis. Active skin lesions on the trunk and limbs were present on less than 10% of the total body surface in 27 patients, 10% to 50% of the body surface in 10 patients, and more than 50% of the body surface in 14 patients.

We prepared a . . . [Full Text of this Article]


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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Topical Tacrolimus
Rapaport
Arch Dermatol 2005;141:1468-1468.
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