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Yoshiyasu Itoh, MD; Yoshiharu Ninomiya, MD; Shingo Tajima, MD; Akira Ishibashi, MD
From the Department of Dermatology, National Defense Medical College, Tokorozawa, Japan.

Arch Dermatol. 2000;136:1093-1095.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF A CASE

A 24-year-old Japanese woman presented with a 10-year history of intractable acne vulgaris lesion on her face. The lesions coincided with her menstrual cycle, and resisted various treatments including 1% nadifloxacin cream, clindamycin hydrochloride lotion, and chemical peeling with glycolic acid and other agents.

THERAPEUTIC CHALLENGE

Our aim was to find an effective and safe treatment for intractable acne vulgaris.

SOLUTION

After obtaining informed consent, the patient was treated with topical 5-aminolevulinic acid photodynamic therapy (ALA-PDT). Twenty percent ALA (A 7793; Sigma, St Louis, Mo) in an oil-in-water emulsion (Yoshida, Tokyo, Japan) was applied to a 5 x 5-cm area of the right cheek for 4 hours with a light-shielded dressing. On Wood lamp examination, the affected lesion showed numerous dots of vivid red fluorescence corresponding to pilosebaceous units in a 5 x 5-cm² square pinkish fluorescence area. The lesion was . . . [Full Text of this Article]

COMMENT

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