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Arch Dermatol. 2000;136:1141-1142.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Reactivation of genital herpes simplex virus type 2 infection in asymptomatic seropositive persons
Wald A, Zeh J, Selke S, Warren T, Ryncarz AJ, Ashley R, Krieger JN, Corey L
N Engl J Med. 2000;342:844-850

Roughly 25% of adults in the United States are estimated to be herpes simplex virus 2 (HSV-2) seropositive, but only 10% to 25% of HSV-2–seropositive individuals have a known history of recognized genital lesions. It has been generally assumed that asymptomatic HSV-2–seropositive individuals not only have less frequent and less severe recurrences but also are less likely to have asymptomatic viral shedding. Two observations, however, suggest evidence contrary to this belief. First, HSV-2–seropositive individuals who do not have a history of genital lesions do notice that they have recurrent episodes once they are educated about the clinical signs and symptoms of HSV infections. Second, most HSV-2 infections are acquired from partners who lack a history . . . [Full Text of this Article]

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