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A Black Necrotic Skin Lesion in an Immunocompromised Patient
K. Adriaenssens, MD;
P. G. Jorens, MD, PhD;
L. Meuleman, MD;
W. Jeuris, MD;
J. Lambert, MD, PhD
University Hospital of Antwerp, Antwerp, Belgium
Arch Dermatol. 2000;136:1165-1170.
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REPORT OF A CASE
A 66-year-old white woman presented with a black necrotic ulcer on the lateral aspect of her face. The lesion had developed over 6 days, beginning as an erythematous plaque. The patient's medical history included a renal transplantation 2 months before the lesion appeared, and her medications included cyclosporine, azathioprine, and prednisolone. There was no history of trauma to her face.
Physical examination revealed a large 3.5-cm necrotic ulcer with an erythematous border on the patient's face, next to her left eye (Figure 1). Routine laboratory investigations showed a C-reactive protein level of 20.4 mg/dL (reference value, <0.5 mg/dL) and a white blood cell count of 4.6 x 109/L (reference range, 4.0-10.0 x 109/L). The patient's fasting blood glucose level was 8.7 mmol/L (156 mg/dL). Two biopsy specimens from . . . [Full Text of this Article]
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