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In a recent issue of the ARCHIVES, Asawanonda et al¹ reported a dose-response study with a 308-nm excimer laser for the treatment of psoriasis. The authors cited our earlier work,² mentioning that we "established some efficacy for excimer laser-generated 308-nm radiation in the treatment of psoriasis," and that we concluded that psoriasis required 7 to 11 treatment sessions to clear.

Indeed, we did provide the first evidence that the 308-nm xenon chloride laser was highly effective for the treatment of psoriasis. However, our real conclusion was that this laser light was more effective than the 311-nm narrow-band UV-B (NB-UVB) treatment in psoriasis. We found that the number of treatments, the duration of the phototherapy, and, probably most importantly, the cumulative UV-B dose were much lower in the xenon chloride laser–treated plaques than in the NB-UVB–treated lesions.

The stepwise increase of the UV-B doses (starting with 0.5 x the minimal erythema . . . [Full Text of this Article]

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

308-nm Excimer Laser for the Treatment of Scalp Psoriasis
Gupta and Taylor
Arch Dermatol 2004;140:518-520.
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