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Erythematous Nodule on a Woman's Face
Lydia A. Juzych, MD;
Catherine A. Nordby, MD
Henry Ford Health System, Detroit, Mich
Arch Dermatol. 2001;137:1367-1372.
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REPORT OF A CASE
An 84-year-old white woman presented with a 3-week history of an asymptomatic, rapidly growing, red-violet, firm nodule on the right side of her nose. The lesion had previously been treated with oral antibiotics as a presumed cyst. The patient was otherwise healthy.
Physical examination revealed a 2-cm, rapidly growing, erythematous to violaceous, firm, solid mass involving the full thickness of the right nasal ala (Figure 1). There was no ulceration or cervical lymphadenopathy.
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Figure 1.
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A diagnostic biopsy specimen was obtained (Figure 2 and Figure 3).
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Figure 2.
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Figure 3.
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What is your diagnosis?
Diagnosis: Merkel cell carcinoma.
Microscopic examination showed a dermal neoplastic infiltrate composed of sheets of small, round cells, arranged in a rosettelike fashion, compressing the epidermis. The individual cells contained scant cytoplasm and powdery chromatin, suggesting a carcinoma of neuroendocrine origin. Numerous mitotic figures were identified. Immunohistochemical stains . . . [Full Text of this Article]
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ABSTRACT
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