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Asymptomatic Papules on a Child
LT Mina D. Jackson, MC, USN;
MAJ Laura Pratt, MC, USA;
LCDR Pat Lawson, MC, USN
Naval Medical Center Portsmouth, Portsmouth, VA
Arch Dermatol. 2001;137:1647-1652.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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REPORT OF A CASE
A 7-year-old healthy white girl presented to the clinic with a several-month history of asymptomatic, firm, flesh-colored, 1-mm papules clustered on the dorsal aspect of her hands (Figure 1). Approximately 1 year later, the lesions had spread to include extensor surfaces of all extremities and her face. Many lesions were crusted. A punch biopsy specimen was obtained for routine microscopic study (Figure 2 and Figure 3).
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Figure 1.
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Figure 2.
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Figure 3.
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What is your diagnosis?
Diagnosis: Perforating granuloma annulare (PGA).
Routine hematoxylin-eosin–stained slides showed a dome-shaped, umbilicated lesion with a central erosion. Collections of histiocytes and sparse perivascular infiltrates of lymphocytes were present within the dermis directly underlying the erosion. In the deeper aspects of the dermis, there was a rare focus where the histiocytes formed a palisading granuloma.
A therapeutic trial of hydroxychloroquine . . . [Full Text of this Article]
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