The objective of this study was to assess the use of epiluminescence light microscopy (ELM) for monitoring antiscabietic therapy. We examined (1) the mite's morphological changes in vivo, (2) the temporal progression of these changes, and (3) their effectiveness as criteria for treatment.
Patients and Methods
Twenty patients were observed (aged 1-82 years). Eleven adult patients showed the typical distribution of burrows; 3 adults and 4 children (aged 1-3 years) had additional palmoplantar burrows; and 2 adult patients had generalized scabies.
Seven patients received 12 mg of ivermectin (Stromectol; MSD-Chibret, Paris, France) as a single dose. Thirteen patients were treated with lindane or benzyl benzoate for 3 days. One recurrent infestation occurred, probably due to treatment failure.
High-resolution ELM was performed using a standard light microscope (ie, a microscope lens in combination with an eyepiece was placed directly on the skin surface). The primary magnification was x8.25 and x20.8, respectively. Photographs . . . [Full Text of this Article]
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