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Curt P. Samlaska, MD
University of Nevada School of Medicine, Henderson

Arch Dermatol. 2001;137:219-224.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF A CASE

A 44-year-old man presented with a lifelong history of an enlarged toe, requiring him to cut out portions of his shoes to obtain a comfortable fit. On physical examination, he had a hypertrophic right fourth toe (Figure 1) and soft tissue proliferation extending approximately 1 cm onto the dorsal aspect of the foot. There was a 5-cm cerebriform mass involving the plantar surface of the fourth and fifth toes (Figure 2). A velvety plaque was localized to the dorsal aspect of the afflicted toe only. An x-ray film showed exostoses involving the fourth metatarsal and phalangeal bones (Figure 3). A deep punch biopsy specimen was obtained (Figure 4).

Figure 1.

Figure 2.

Figure 3.

Figure 4.

What is your diagnosis?

Diagnosis: Proteus syndrome

The punch biopsy specimen from the dorsal aspect of the toe demonstrated acanthosis, papillomatosis, and hyperkeratosis. The collagen . . . [Full Text of this Article]

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