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  Vol. 137 No. 3, March 2001 TABLE OF CONTENTS
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  The Cutting Edge: Challenges in Medical and Surgical Therapeutics
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 •Dermatology
 •Dermatologic Disorders
 •Bullous Diseases
 •Pemphigus
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Anti-CD20 Monoclonal Antibody (Rituximab) for Refractory Erosive Stomatitis Secondary to CD20+ Follicular Lymphoma–Associated Paraneoplastic Pemphigus

Luca Borradori, MD; Tommaso Lombardi, MD, DMD; Jacky Samson, MD; Christophe Girardet, MD; Jean-Hilaire Saurat, MD; Anne Hügli, MD
From the University Hospital, Geneva, Switzerland.

Arch Dermatol. 2001;137:269-272.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF A CASE

A 61-year-old white woman was referred in April 1999 with a 6-week history of extremely painful and severe erosive stomatitis accompanied by asthenia, difficulty in eating, and weight loss. Her medical history was unremarkable except for taking atenolol and chlorthalidone for arterial hypertension and hormone replacement therapy. Results of clinical examination revealed fibrin-covered shallow coalescing ulcers on the buccal mucosa, lower labial mucosa, the anterior region of floor of the mouth, and the dorsum and undersurface of the tongue (Figure 1). The initial lesions appeared as red macules followed by erosions. The vermilion of the lips showed extensive erosions and crusting. She also had some isolated 2- to 5-mm erythematous blue maculopapular and slight hyperkeratotic lesions on the palms.


 
Figure appears in full text version.
Figure 1. Large ulcerations covered by fibrin sloughs on the . . . [Full Text of this Article]


THERAPEUTIC CHALLENGE

SOLUTION

COMMENT



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