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A Case of Trichloroethylene Hypersensitivity Syndrome
Anthony T. Goon, MD;
Lay-Tin Lee, MD;
Yong-Kwang Tay, MD;
Gil Yosipovitch, MD;
See-Ket Ng, MD;
Yoke-Chin Giam, MD
Arch Dermatol. 2001;137:274-276.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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REPORT OF A CASE
A 36-year-old Chinese man presented with a 6-day history of fever, a 5-day history of a generalized erythematous maculopapular rash, a 4-day history of red sore eyes, and a 3-day history of sore lips. He did not have any history of ingestion of medications or herbs.
Physical examination revealed a generalized erythematous maculopapular rash, which gradually became confluent and dusky, but was still blanchable. No blisters were seen at presentation. There were extensive moist erosions on the patient's lips, buccal mucosa, and oropharynx. There was bilateral conjunctival injection, which the ophthalmologist diagnosed as pseudomembranous conjunctivitis. There was no hepatosplenomegaly.
Histologic examination of the patient's skin showed subepidermal clefting and bulla formation, with necrotic keratinocytes in the middle and lower epidermis. Vacuolar degeneration was evident in the basal layer, and there was . . . [Full Text of this Article]
DIAGNOSTIC CHALLENGE
COMMENT
From the National Skin Centre (Drs Goon, Tay, Yosipovitch, Ng, and Giam) and Occupational Health Department, Ministry of Manpower (Dr Lee), Singapore.
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