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Successful Treatment of Erosive Lichen Planus With Topical Tacrolimus
Elizabeth V. Lener, MD;
Joaquin Brieva, MD;
Marianne Schachter, MD;
Lee E. West, BS, RPh;
Dennis P. West, PhD
Northwestern University Medical School, Chicago, Ill
Rokea A. el-Azhary, MD
Mayo Clinic and Mayo Clinic Foundation, Rochester, Minn
Arch Dermatol. 2001;137:419-422.
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REPORT OF A CASE
A 69-year-old woman with a history of colon carcinoma, cirrhosis of the liver secondary to hepatitis C, and erosive oral lichen planus presented to the dermatology clinic for therapeutic options regarding a growing ulceration on her lower lip. In the past year, the ulceration had enlarged and she had begun to develop new, painful, shallow ulcerations in the oral mucosa. In addition, she complained of intermittently pruritic papules involving the distal volar surfaces of her forearms. Biopsies and direct immunofluorescence were performed to evaluate histopathological features. The patient was diagnosed with erosive oral and cutaneous lichen planus. The cutaneous lesions resolved on treatment with fluocinonide cream. However, the lip and oral ulcerations persisted despite topical application of fluocinonide and clobetasol propionate gel once or twice daily for . . . [Full Text of this Article]
THERAPEUTIC CHALLENGE
SOLUTION
COMMENT
RELATED ARTICLE
Editor's Comment
Elaine Siegfried
Arch Dermatol. 2001;137(4):422.
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