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Andrea Pestarino, MD; Susanna Borghi, MD; Marih Dezzana, MD; Marco Canepa, MD; Luigi Massone, MD
Galliera Hospital, Genoa, Italy

Arch Dermatol. 2001;137:657-662.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF A CASE

A 45-year-old man presented for evaluation of a slowly growing, ill-defined area of alopecia localized on the lower part of his left leg. The lesion had been present for 2 years. Physical examination revealed a 5 x 10-cm asymptomatic area of alopecia studded with follicular keratotic papules (Figure 1). There was no lymphadenopathy, and the results of the rest of the physical examination were normal. A biopsy was performed (Figure 2).

Figure 1.

Figure 2.

What is your diagnosis?

Diagnosis: Follicular mycosis fungoides.

Microscopic examination of the biopsy specimen revealed a dense lymphocytic infiltrate of the superficial dermis, with marked involvement of the perifollicular dermis and follicular epithelium ("folliculotropism"). No epidermotropism was present. The infiltrate was monomorphous and composed of atypical UCHL-1 (CD-45RO)– and CD4-positive lymphocytes; some nuclei were hyperchromatic and cerebriform. Eosinophils and plasma . . . [Full Text of this Article]

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