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We report the successful treatment of multiple verrucae planae in a 42-year-old man with topical application of 5% imiquimod cream. Imiquimod is a new immune response modifier for local application that induces the release of cytokines including interferon alfa, tumor necrosis factor , and certain interleukins by peripheral mononuclear blood cells and lymphocytes.¹

Clinical trials have shown a greater efficacy and safety of imiquimod for the treatment of external genital warts induced by human papilloma virus and a lower recurrence rate compared with other treatment options.² Based on these findings and the similarity of the etiologic origin to verrucae planae, which show a close relationship to human papilloma virus types 3 and 10, we decided to treat this patient with imiquimod.

He had multiple verrucae planae on his fingers, the backs of his hands (Figure 1), and his lower arms for more than 2 years. His general condition . . . [Full Text of this Article]

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Topical Imiquimod in the Treatment of Metastatic Melanoma to Skin
Wolf et al.
Arch Dermatol 2003;139:273-276.
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