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Cutaneous Leishmaniasis Due to Leishmania infantum in the Northeast of Spain: The Isoenzymatic Analysis of Parasites
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Human cutaneous leishmaniasis (HCL) has been known in Spain since 1914, when it was described in the Alpujarras region (Andalusia). The causative agent was characterized in 1986 for the first time by isoenzyme electrophoresis and identified as a zymodeme of Leishmania infantum.1 Further studies showed the enzymatic polymorphism of L infantum in HCL, which we now report in Catalonia.
Ten Leishmania isolates from 8 patients with cutaneous and mucocutaneous leishmaniasis acquired in Catalonia were collected between 1984 and 1996 and identified by isoenzyme electrophoretic analysis in starch gel using 15 loci.2 Characteristics of the patients and isoenzyme identification are given in Table 1.
Table appears in full text version.
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List of Strains, Characteristics of Patients, and Zymodemes Identified*
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First reports on infraspecific identification of L infantum in the Mediterranean region revealed the existence of various zymodemes more or less related to clinical patterns of the disease. Therefore, L infantum zymodemes in the Mediterranean region . . . [Full Text of this Article]
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Am J Trop Med Hyg 2007;76:888-895.
ABSTRACT
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An Unusual Presentation of Cutaneous Leishmaniasis
Anton et al.
Arch Dermatol 2005;141:109-110.
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