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Ulrich R. Hengge, MD; Roxana Stark, MD
From the University of Essen, Essen, Germany.

Arch Dermatol. 2001;137:709-711.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF CASES

CASE 1

An 82-year-old man with severe cardiac arrhythmia and recurrent heart failure presented with a 3-year history of erythematous plaques on the left orbita and on the chest. The lesion on his left eye was a hypertrophic actinic keratosis (2 x 1.5 cm), a scaly erythematous plaque on the saddle of the nose extending to the opening of the left lacrimal duct. The chest lesion consisted of a 5 x 2.5-cm plaque with a hemorrhagic crust that caused recurrent itching. On histologic examination, the epidermal cells in the lower epidermis were atypical and showed large, hyperchromatic nuclei and abnormal mitoses (Figure 1A). The biopsy specimen tested positive for human papillomavirus (HPV) type 33 using consensus primers and polymerase chain reaction.¹

Figure appears in full text version. Figure 1. A, Histological examination of patient 1 revealed epidermal keratinocytes with large hyperchromatic nuclei and atypical mitoses in several layers of . . . [Full Text of this Article]

CASE 2

THERAPEUTIC CHALLENGE

SOLUTION

COMMENT



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