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Brian M. Matthys, DO; Stephen C. Somach, MD
Cuyahoga Falls General Hospital, Cuyahoga Falls (Dr Matthys), and MetroHealth Medical Center Campus, Case Western Reserve University, Cleveland (Dr Somach), Ohio

Arch Dermatol. 2001;137:815-820.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF A CASE

A 50-year-old white man presented with a 1-month history of an asymptomatic 1.3-cm brown-yellow crusted nodule on the right side of his lower lip (Figure 1). He reported trauma to the area from recent dental work. An incisional biopsy of the nodule was performed (Figure 2 and Figure 3).

Figure 1.

Figure 2.

Figure 3.

What is your diagnosis?

Diagnosis: Eosinophilic ulcer of the oral mucosa (EUOM).

A punch biopsy specimen from the central portion of the lesion was broadly ulcerated and contained a diffuse, heavy, inflammatory cell infiltrate. High-power view of the base of the lesion revealed an infiltrate composed of lymphocytes, histiocytes, plasma cells, and numerous eosinophils extending around skeletal muscle bundles. The histiocytic cells did not react to immunoperoxidase staining with antibodies to S100 protein or CD30.

Our patient was treated with 0.05% clobetasol propionate ointment twice daily, which he used on an . . . [Full Text of this Article]

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