Cutaneous Warts in HIV-Positive Patients Undergoing Highly Active Antiretroviral Therapy
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Cutaneous warts in patients with human immunodeficiency virus (HIV) are prevalent and respond poorly to conventional treatment. Recent studies suggest that highly active antiretroviral therapy (HAART) is associated with wart regression (unpublished data, November 2000).1 The purpose of this study was to determine whether immune reconstitution plays a role in the natural history of cutaneous warts in HIV-positive individuals.
Patients and Methods
This is a prospective cohort study that included 12 HIV-positive patients (primarily homosexual white men) with a clinical diagnosis of cutaneous warts. All patients underwent 3 examinations at the San Francisco General Hospital Dermatology Clinic from 1996 through 1999. This period was selected because it is when the patients began HAART, which is defined as a combination therapy with 2 nucleoside reverse transcriptase inhibitors and either 1 protease inhibitor or 1 nonnucleoside reverse transcriptase inhibitor.
The original diagnosis was based on retrospective review of the charts of patients who had documented . . . [Full Text of this Article]
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