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Treatment of Kaposi Sarcoma With Oral Administration of Shark Cartilage in a Human Herpesvirus 8–Seropositive, Human Immunodeficiency Virus–Seronegative Homosexual Man
Joseph D. Hillman, BS;
Albert T. Peng, MD;
Anita C. Gilliam, MD, PhD;
Scot C. Remick, MD
From the Departments of Pathology (Mr Hillman) and Dermatology (Drs Peng and Gilliam) and the Division of Hematology/Oncology in the Department of Medicine (Dr Remick), University Hospitals of Cleveland, Case Western Reserve University, Cleveland, Ohio.
Arch Dermatol. 2001;137:1149-1152.
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REPORT OF A CASE
A 45-year-old white man presented with a 2 -year history of a bruiselike area on the arch of his right foot (Figure 1). A skin biopsy specimen of the lesion revealed Kaposi sarcoma (KS) (Figure 2), with slitlike vascular spaces that were accentuated by CD34 immunostaining (Figure 3).
Figure appears in full text version.
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Figure 1. A, Erythematous patch of Kaposi sarcoma on the patient's right mid instep in 1997. B, Patch has faded significantly in color by 1999.
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Figure appears in full text version.
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Figure 2. Sections of skin in 1997 (A) and 1999 (B) showing decreased numbers of small vessels in papillary dermis (hematoxylin-eosin, original magnification x40).
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Figure appears in full text version.
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Figure 3. Immunostaining for CD34 to accentuate vessels of Kaposi sarcoma shows diminished numbers and prominence of vascular spaces in 1997 (A) compared with 1999 (B). Immunostaining was performed . . . [Full Text of this Article]
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THERAPEUTIC CHALLENGE
SOLUTION
COMMENT
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