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More Data and New Aspects

Arch Dermatol. 2002;138:112-113.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

IN THE August 2001 issue of the ARCHIVES, Wiseman et al¹ presented new and interesting data obtained from a group of 148 consecutive patients who were treated with diphencyprone. The authors provide convincing evidence that this therapeutic modality is associated with a high rate of satisfactory responses that cannot be equaled by any other known treatment.

I agree with the authors that the large range of success rates published in previous studies can be attributed to a lack of uniform definition for "response." Wiseman et al defined a clinically substantial response as "significant regrowth resulting in greater than 75% of the scalp being covered with terminal hair (as determined by the investigators)."

A great advantage of this study is that the patients were homogeneously distributed among 4 different groups showing 25% to 49% hair loss, 50% to 75% hair loss, 75% to 99% hair loss, and 100% hair loss. If . . . [Full Text of this Article]

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