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Yukiko Tsuji, MD; Toshimitsu Kawashima, MD, PhD; Koichi Yokota, MD, PhD; Yasuki Tateish, MD; Yuki Tomita, MD; Tetsuri Matsumura, MD, PhD; Hiroshi Shimizu, MD, PhD

Arch Dermatol. 2002;138:95-96.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

INTRODUCTION

Several cases in which the disease course has undergone a transition from pemphigus vulgaris (PV) to pemphigus foliaceus (PF) or vice versa have been reported in the literature. The disease transition in these cases was determined by means of clinical and histopathological observations and immunoblot analysis. To our knowledge, the case described herein represents the first report to clearly demonstrate the serological transition from mucous PV to mucocutaneous PV to PF using a desmoglein (Dsg) enzyme-linked immunosorbent assay (ELISA) system.

REPORT OF A CASE

A 55-year-old Japanese man presented to our outpatient clinic in March 1997 with a 3-month history of intractable oral erosions (Figure 1A). Clinical, histopathological, and immunological findings led to the diagnosis of PV. Using a Dsg ELISA system (Dsg1/3 ELISA kit; Medical & . . . [Full Text of this Article]

COMMENT

From the Department of Dermatology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.

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