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Arch Dermatol. 2002;138:1591-1592.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

THE ARTICLE by Cordain et al¹ in this issue of the ARCHIVES represents an interesting departure for a contemporary, peer-reviewed medical journal. While the present-day emphasis is on controlled, double-blinded clinical studies that pass the muster for evidence-based medicine, the report by Cordain et al is observational, and the only control is the dietary limitations characteristic of 2 isolated nonwesternized populations.

These authors suggest that the absence of acne in more than 1300 subjects in 2 nonwesternized societies—the Kitavan Islanders of Papua New Guinea and Aché hunter-gatherers of Paraguay—is attributable to their diets, which have a substantially lower glycemic index than a Western diet. In addition, these people are more physically active than Westerners. They do not demonstrate insulin resistance, nor do they have obesity, hypertension, diabetes, or heart disease. Their genetic background is similar to other Pacific Islanders and South American Indians, respectively, yet their incidence of acne is . . . [Full Text of this Article]

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