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New Insights Into an Old Problem

Arch Dermatol. 2002;138:244-246.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

MYCOSIS FUNGOIDES (MF), as first described by Alibert¹ during the 19th century, is now simply defined as an indolent CD4⁺ non-Hodgkin lymphoma that affects the skin primarily with erythematous patches, plaques, and tumors. Nevertheless, many subtypes of MF have been identified (eg, granulomatous MF,² hyperkeratotic MF,³ hypopigmented MF,⁴ MF associated with follicular mucinosis,⁵ MF bullosa,⁶ MF palmaris et plantaris,⁷ granulomatous slack skin,⁸ and pagetoid reticulosis⁹), each nominally with its own set of clinical and histologic presentations.¹⁰

It is clear that some of these subtypes are only minor variants of MF and should not be considered distinct entities. However, a few possess features that make them eligible for consideration, if not as individual diseases, at least as major MF variants with their own clinical, pathologic, and immunohistologic characteristics. One of these subtypes is so-called pagetoid reticulosis, described by Woringer and Kolopp¹¹ in 1940. This disease presents clinically with erythematous, scaly, . . . [Full Text of this Article]

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