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A Variant of Reactive Angioendotheliomatosis Associated With Peripheral Vascular Atherosclerosis

Sam Kim, MD; Rosalie Elenitsas, MD; William D. James, MD

Arch Dermatol. 2002;138:456-458.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF A CASE

A 58-year-old African American woman with a history of hypertension, insulin-dependent diabetes mellitus, and heavy tobacco use presented with a 3-month history of an ulcer on her left thigh. On review of her systems, an intermittent claudication in both legs was noted. Physical examination revealed a 3 x 5-cm ulcer within a 10 x 15-cm firm, red-violaceous plaque on the left medial-posterior thigh (Figure 1). Peripheral pulses in the bilateral lower extremities were not palpable. A biopsy specimen of the left thigh plaque revealed a dense proliferation of uniform spindle cells in the papillary and upper reticular dermis forming small vascular spaces (Figure 2, A and B). When examined with immunoperoxidase staining, the spindle cells stained positively with vascular markers CD31 and CD34 (Figure 2C). These cells were closely associated with cells staining positively . . . [Full Text of this Article]

DIAGNOSTIC CHALLENGE

COMMENT

From the Department of Dermatology, University of Pennsylvania, Philadelphia.

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ABSTRACT | FULL TEXT