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Arch Dermatol. 2002;138:521-522.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

THE LOOSE anagen hair syndrome (LAS) is a sporadic or familial hair disorder that primarily affects children but may occasionally be seen in adults.^1-8 The condition is due to a defective anchorage of the hair shaft to the follicle, resulting in easily and painlessly pluckable hair. Patients with LAS complain of slow-growing hair and diffuse or patchy alopecia. The clinical manifestations of the disorder are in most cases mild, and it is likely that only a small proportion of children with the condition seek dermatological advice.

The diagnosis of LAS is based currently on the microscopic identification of the typical loose anagen hair (LAH) that is devoid of sheaths. Such hair is not, however, a reliable marker of LAS because it may also be present in hair samples from normal children and adults. The most important problem in diagnosing LAS is that the weak hair shaft–hair follicle adhesion characterizing the . . . [Full Text of this Article]

EPIDEMIOLOGY


CLINICAL FEATURES

DIAGNOSIS

PATHOGENESIS

PROGNOSIS

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Is the Loose Anagen Hair Syndrome a Keratin Disorder?: A Clinical and Molecular Study
Valérie Chapalain, Hermelita Winter, Lutz Langbein, Jean-Michel Le Roy, Christine Labrèze, Milos Nikolic, Jürgen Schweizer, and Alain Taïeb
Arch Dermatol. 2002;138(4):501-506.
ABSTRACT | FULL TEXT