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Alopecia, Hypohidrosis, and Ulcerations in a Man
Heidi F. Hoefer, MD;
San-Hwan Chen, MD;
Madeleine A. Duvic, MD;
Sharon S. Raimer, MD
University of Texas Medical Branch, Galveston (Drs Hoefer, Chen,
and Raimer), and M. D. Anderson Cancer Center, Houston, Tex (Dr Duvic)
Arch Dermatol. 2002;138:527-532.
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REPORT OF A CASE
A 46-year-old man presented with a 20-year history of dry skin. Approximately
5 years earlier, he had begun noticing hair loss, starting with the eyebrows
and eyelashes, which had progressed to involve his scalp and entire body.
Three years before presentation, he noticed an absence of sweating except
on his knuckles. Ulcerations, preceded by dry, erythematous skin, developed
on his buttocks and extended to his trunk and extremities. He denied any other
health problems, and a review of systems revealed no abnormalities.
Physical examination revealed hair loss over the patient's entire body,
with a few patches of sparse hair growth on the scalp (Figure 1) and right leg. Generalized erythematous, scaly plaques
with numerous excoriations were present on the face, trunk, and extremities.
Multiple erythematous, reticulated patches with punched-out ulcerations (Figure 2. . . [Full Text of this Article]
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