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Metastatic Silicone Granuloma: Lupus Miliaris Disseminatus Faciei–like Facial Nodules and Sicca Complex in a Silicone Breast Implant Recipient
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Silicone granulomas are usually observed near silicone-injected areas.1-2 We describe a patient in whom
breast-injected silicone was delivered to multiple organs, including facial
skin, salivary glands, bone marrow, and lymph nodes, and caused granulomatous
lesions. The patient complained of various signs and symptoms suggestive but
not diagnostic of a connective tissue disease, and making a definitive diagnosis
was difficult.
Report of a Case
A 56-year-old Japanese woman was admitted to our hospital (Nippon Medical
School, Tokyo) on January 12, 1999, complaining of symptomatic eyelid edema
and erythema on her face and arms. She was first diagnosed as having dermatomyositis,
although she did not complain of any muscle weakness. Two weeks later, she
began to notice Sjögren syndrome–like annular erythema on both
arms. Sicca complex, dry mouth and dry eyes (Schirmar test: right eye, 1 mm;
left eye, 0 mm), and progressive loss of sweating on her forehead also appeared.
Results of repeated laboratory studies, . . . [Full Text of this Article]
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