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Thin Melanomas and Regression, Thick Melanomas and Older Men
Prognostic Implications and Perspectives on Secondary Prevention
Arch Dermatol. 2002;138:678-682.
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IN THIS issue of the ARCHIVES, the members of the North American Melanoma
Pathology Study Group report on the histological characteristics of thin metastasizing
melanomas.1 The North American Melanoma Pathology
Study Group is composed of pathologists from the United States and Canada;
this group meets twice a year to review specific issues in regard to the pathological
aspect of pigmented lesions and melanoma. Their study showed that thin melanomas
with extensive regression represented a group at higher risk for metastasis.
The investigators searched electronic records from melanoma databases and
pathology departments at 8 academic centers and identified 43 patients with
a melanoma smaller than 1.0 mm and a known history of metastases. All the
metastases were confirmed by histological examinations. From each melanoma
case, representative slides were independently reviewed by a panel of 10 dermatopathologists
experienced in pigmented lesions. The control group included 42 patients with
thin melanomas, with no . . . [Full Text of this Article]
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