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Lower Extremity Purpura
Joshua M. Berlin, MD;
John R. Queen, MD
Cleveland Clinic Foundation, Cleveland, Ohio
Arch Dermatol. 2002;138:831-836.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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REPORT OF A CASE
A 24-year-old white woman presented to the emergency department with
a 3-day eruption on her lower extremities. Her medical history was remarkable
for paroxysmal nocturnal hemoglobinuria that had been diagnosed 10 years earlier;
frequent transfusions have been required for this condition, with the last
one being administered 10 days before presentation. She frequently developed
hives after transfusion and thought that the present eruption was a variant
of her usual hives. Petechiae initially developed on her right ankle, followed
by scattered purpuric patches on her left ankle and shin.
Physical examination at the time of presentation revealed nontender,
nonblanchable, palpable purpura scattered on both legs (Figure 1 and Figure 2). A 3-mm punch biopsy specimen was obtained (Figure 3 and Figure 4).
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Figure 1.
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Figure 2.
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Figure 3.
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Figure 4.
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What is your diagnosis?
Diagnosis: Paroxysmal nocturnal hemoglobinuria-induced purpura.
The biopsy specimen revealed an . . . [Full Text of this Article]
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