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Jaeyoung Yoon, MD, PhD; Daniel J. Santa Cruz, MD; Roberta D. Sengelmann, MD
Washington University School of Medicine (Drs Yoon, Santa Cruz, and Sengelmann) and Cutaneous Pathology (Dr Santa Cruz), St Louis, Mo

Arch Dermatol. 2002;138:831-836.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF A CASE

A 72-year-old white woman presented with a 6-month history of an erythematous plaque on the left nasal tip. Initially, she was treated for suspected rosacea with oral minocycline hydrochloride (100 mg/d) and 0.75% metronidazole topical cream (once a day), without benefit. The lesion persisted and began growing rapidly over the couple of months before her presentation to the dermatology clinic.

On physical examination, there was a 3.4 x 2.8-cm, erythematous, slightly hyperkeratotic and boggy plaque with an irregular border that was not tender to palpation (Figure 1). There was no head or neck lymphadenopathy, and no nasal or oral mucosal involvement was noted. A biopsy specimen was obtained (Figure 2).

Figure 1.

Figure 2.

What is your diagnosis?

Diagnosis: Angiosarcoma.

The biopsy specimen revealed an infiltrate of atypical epithelioid cells forming anastomosing channels and dissecting . . . [Full Text of this Article]

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