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In the July 2001 issue of the ARCHIVES, Marghoob et al¹ describe agminated dysplastic nevi in a patient who had, in addition, numerous disseminated dysplastic and nondysplastic melanocytic nevi. The authors may be quite right in assuming that the agminated lesions, being superimposed on the disseminated, nonsegmental phenotype, resulted from loss of heterozygosity for one of the various genes responsible for the development of multiple melanocytic nevi.²

The authors were unable to find a previous report on agminated atypical (dysplastic) nevi. They are stating that "agminated as it pertains to melanocytic nevi is defined as circumscribed grouping of pigmented lesions confined to a body segment." According to this definition, their case would not be unique because Sterry and Christophers³ reported on quadrant distribution of multiple dysplastic nevi, associated within the same quadrant with multiple lentigines and typical acquired melanocytic nevi as well as 2 malignant melanomas. Similarly, Misago et . . . [Full Text of this Article]