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Verrucous Plaque in a Cardiac Transplant Recipient
Yi-Hua Liao, MD;
Nai-Kuan Chou, MD;
Hsien-Ching Chiu, MD;
Shoei-Shen Wang, MD
National Taiwan University Hospital, Taipei
Arch Dermatol. 2002;138:973-978.
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REPORT OF A CASE
A 62-year-old man underwent cardiac transplantation because of ischemic
cardiomyopathy. His immunosuppressive regimen included cyclosporin, azathioprine
sodium, and prednisolone. His postoperative course was uneventful, and no
significant rejection occurred. One year after surgery, the patient presented
with a 1-month history of a rapidly enlarging lesion on the dorsal aspect
of his right hand. Physical examination revealed a 9 x 6-cm, erythematous,
fluctuant, verrucous plaque with some overlying purulent crust
(Figure 1). Pus was elicited when the lesion was squeezed, but no
granules were seen. The patient was afebrile, and he denied any trauma to
the affected region.
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Figure 1.
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A biopsy specimen was obtained for histopathologic examination and culture.
The specimen was stained with hematoxylin-eosin
(Figure 2) and periodic acid–Schiff
(Figure 3), and the fungal culture was stained with lactophenol cotton blue
. . . [Full Text of this Article]
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