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Pyloric Stenosis and Pyloric Atresia: The Same Pathogenesis?
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| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
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I read with interest the article by Dereure et al1
that appeared in the "Vignettes" section of the May 2001 issue of the ARCHIVES
in which they report a case of dystrophic epidermolysis bullosa associated
with congenital absence of skin and pyloric stenosis. I partly disagree with
the comment on this case. Pyloric stenosis is actually not a minor form of
atresia. Infantile pyloric stenosis, or congenital hypertrophic pyloric stenosis,
is a relatively common disorder with a high familial incidence as well as
a marked male predominance. Its pathogenesis remains unclear. This condition
requires abdominal surgery in the first few months of life. In contrast, pyloric
atresia is rare. Atresia is classified according to 3 types.2
The congenital mucosal membrane type, which is the most common variant, consists
of webs and diaphragms, but in epidermolysis bullosa associated with pyloric
atresia, the longitudinal segmental variant of atresia predominates.2 Pathological examination of . . . [Full Text of this Article]
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