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Alopecia Universalis Completely Resolved Following Autologous Bone Marrow Transplantation
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Alopecia universalis (AU) is a disease characterized by a nonscarring,
total body hair loss of unknown etiology. It is associated with other autoimmune
diseases and serum autoantibodies, and abnormalities on complement function
are sometimes detected.1-2
In this article, we relate a case of persistent hair regrowth following high-dose
chemotherapy and autologous stem cell transplantation (ASCT) for a non-Hodgkin
lymphoma in a patient with extensive AU.
Report of a Case
A 48-year-old man was referred to our service in August 1997 with a
follicular lymphoma (Ann Arbor stage IIIB), diagnosed in July 1995, that was
refractory to chemotherapy. He had been extensively pretreated with different
chemotherapy regimens such as BACOP (bleomycin, doxorubicin, cyclophosphamide,
vincristine, and prednisone), MINE (ifosfamide, mitoxantrone, and etoposide),
and DHAP (dexamethasone, cytarabine, and cisplatin). He also reported a long-lasting
history of AU since age 19 years (Figure 1). He had been treated with topical and systemic corticosteroids
and minoxidil without . . . [Full Text of this Article] Comment
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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Complete remission of alopecia universalis after allogeneic hematopoietic stem cell transplantation
Seifert et al.
Blood 2005;105:426-427.
ABSTRACT
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