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  Vol. 138 No. 9, September 2002 TABLE OF CONTENTS
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  Evidence-Based Dermatology: Research Commentary
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Adult vs Childhood Susceptibility to Melanoma: Is There a Difference?

Arch Dermatol. 2002;138:1234-1235.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Timing of excessive UV radiation and melanoma: epidemiology does not support the existence of a critical period of high susceptibility to solar UV radiation induced melanoma.
Pfahlberg A, Kolmel KF, Gefeller O, for the FEBIM Study Group
Br J Dermatol. 2001;144:471-475

Exposure to solar UV radiation is believed to be the major environmental cause of melanoma. However, controversy exists over whether children are particularly susceptible to melanoma initiation compared with adults.

The objective of the study by Pfahlberg et al was to compare the effects of sun exposure—and in particular episodes of sunburn—in childhood with that in adulthood to determine whether a "critical period" exists in early life. The study was designed as a multicenter, case-control study. Participants included 603 histologically confirmed melanoma cases and 627 population controls in 7 European countries. Controls were frequency matched to the cases with respect to sex, age, and ethnic origin. Study subjects . . . [Full Text of this Article]

Comment

BACKGROUND

SUBJECTS

EXPOSURE ASCERTAINMENT

ANALYSIS

CONCLUSIONS







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