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Arch Dermatol. 2003;139:93-98.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Cutaneous pseudosarcomatous polyp.

MICROSCOPIC FINDINGS

Microscopic examination revealed a paucicellular lesion with polypoid architecture at scanning magnification. The epidermis was slightly acanthotic, but hyperpigmentation of the basal layer was absent. The dermis had an abundant myxoid stroma with scattered, bizarre, often multinucleated, stellate and spindle-shaped stromal cells. The nuclei of these cells were hyperchromatic, but the nucleoli were generally inconspicuous. Mitotic figures were not observed in multiple levels of sectioning. Many of the dilated blood vessels, some containing thrombi, had partially hyalinized vessel walls.

The atypical stellate and spindled stromal cells stained strongly positive with antibody to vimentin and weakly positive with antibody to factor XIIIa. Antibodies to actin and S100 protein showed patchy positive staining. Antibodies to CD34, CD68, and desmin failed to stain the atypical cells.

DISCUSSION

The cutaneous pseudosarcomatous polyp was originally described by Williams et al¹ in 1996. Clinically, the lesions occur as solitary, slow-growing, pedunculated nodules on the trunk or extremities. . . . [Full Text of this Article]

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Arch Dermatol. 2003;139(1):93-98.
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