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  Vol. 139 No. 10, October 2003 TABLE OF CONTENTS
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  The Cutting Edge: Challenges in Medical and Surgical Therapeutics
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Recalcitrant, Recurrent Aphthous Stomatitis Treated With Etanercept

Neha D. Robinson, MD; Joan Guitart, MD
From the Department of Dermatology, Northwestern University Medical School, Chicago, Ill.

Arch Dermatol. 2003;139:1259-1262.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF A CASE

A 50-year-old woman presented with a 24-year history of recurrent aphthous stomatitis. Nine to 12 new lesions usually appeared weekly, resolving in approximately 2 weeks. She experienced associated pain, dysphagia, and swelling of the lips and tongue with a subjective pain severity of 9 (scale, 1-10). Symptoms were exacerbated before menstrual periods and were unchanged with use of oral contraceptives and after menopause. There was no association with food or oral trauma, but she reported flares with emotional stress. She denied associated fever, genital ulcers, skin lesions, or ocular complaints.

On physical examination, there were small erosions (<5 mm) on the left lateral part of the tongue, gingival mucosa, and nonkeratinized labial mucosa, surrounded by erythematous halos (Figure 1).


 
Figure appears in full text version.
Figure 1. Shallow ulcerations on the nonkeratinized labial mucosa before etanercept treatment was started.


A complete blood cell count, levels of serum . . . [Full Text of this Article]

THERAPEUTIC CHALLENGE

SOLUTION

COMMENT



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