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Arch Dermatol. 2003;139:1363-1368.

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Diagnosis: Frontal fibrosing alopecia (FFA), a variant of lichen planopilaris (LPP).

MICROSCOPIC FINDINGS AND CLINICAL COURSE

Horizontal sections showed a decreased number of terminal anagen follicles and an infiltrate of lymphocytes and eosinophils juxtaposed on remaining infundibula, as well as concentric peri-infundibular fibrosis. There was loss of sebaceous lobules.

The patient was treated with intralesional corticosteroids (triamcinolone acetonide [Kenalog]) with significant reduction of her scalp pruritus and subjective slowing of the progression of hair loss. Clinically, there was reduction in perifollicular erythema and scale; anagen hairs remained easily extractable on a hair-pull test.

DISCUSSION

Frontal fibrosing alopecia, a cicatricial alopecia in a characteristic distribution, was first described by Kossard¹ in 1994. Since then, there have been few reports of this entity in the literature.^2-6 The clinical hallmark of FFA is the onset of alopecia in a bandlike distribution along, and anterior to, the frontal hairline of an older woman, frequently accompanied by loss of eyebrows. To date, no similar presentation has been reported in men.

Frontal fibrosing . . . [Full Text of this Article]

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Arch Dermatol. 2003;139(10):1363-1368.
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