This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Related article  • Similar articles in this journal  Topic Collections  • HIV/AIDS  • Dermatology  • Dermatologic Disorders  • Diagnosis  • Dermatologic Disorders, Other  • Infectious Diseases  • Alert me on articles by topic  Social Bookmarking   What's this?

Arch Dermatol. 2003;139:1647-1652.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Cutaneous acanthamebiasis.

MICROSCOPIC FINDINGS AND CLINICAL COURSE

The biopsy specimen showed an extensive lobular panniculitis with a mixed neutrophilic, eosinophilic, and lymphocytic inflammatory infiltrate. A leukocytoclastic vasculitis with focal necrosis was present. Rare enlarged cells (Figure 2, arrow) were found in hematoxylin-eosin–stained sections, which demonstrated abundant vacuolar and granular eosinophilic cytoplasm. Deeper levels in the specimen revealed an elongate and ameboid cell with a villouslike cell surface that had an eccentric nucleus containing a single dense, central nucleolus.

Figure appears in full text version. Figure 2.

A diagnosis of cutaneous acanthamebiasis, an opportunistic infection caused by free-living amoebas of the genus Acanthamoeba, was made. Only trophozoites, and no encysted organisms, were identified in a tissue sample. While a nasal and palatal examination showed that the patient was free of amebic lesions, radiological investigations revealed a pansinusitis. Blood, lung, and soft tissue samples submitted for culture were negative for Acanthamoeba organisms. Magnetic resonance imaging of the patient's brain revealed no enhancing . . . [Full Text of this Article]

DISCUSSION

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

RELATED ARTICLE

Tender Subcutaneous Nodules in a Patient With AIDS—Quiz Case
Liron Pantanowitz, John Williams, Xiaowei Xu, and Steven R. Tahan
Arch Dermatol. 2003;139(12):1647-1652.
EXTRACT | FULL TEXT