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Peter Thomas, MD; Monika Walchner, MD; Kamran Ghoreschi, MD; Martin Röcken, MD
From the Klinik und Poliklinik für Dermatologie und Allergologie der Ludwig-Maximilians-Universität, Munich, Germany.

Arch Dermatol. 2003;139:136-138.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

REPORT OF A CASE

A 39-year-old woman presented with a 5-month history of painless, nonitching swelling of the upper lip (Figure 1). In addition, she had a symptomless lingua plicata. A biopsy specimen revealed cheilitis with edema and perivascular lymphohistiocytic infiltrates (Figure 2) pointing to an early stage of cheilitis granulomatosa (CG). There was no neurologic abnormality such as facial palsy. Also, there were no findings or history of previous infection or local contact allergy. Systemic clofazimine therapy was started at 200 mg/d but discontinued after 2 weeks because of a morbilliform eruption. Over the following 4 months, dapsone therapy at 50 mg/d had no effect. Thereafter, prednisone treatment at 40 mg/d for 10 days reduced the lip swelling but was followed by an immediate recurrence on discontinuing the treatment.

Figure appears in full text version. Figure 1. Patient with edematous enlargement of the . . . [Full Text of this Article]

THERAPEUTIC CHALLENGE

SOLUTION

COMMENT



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