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Urbà González, MD, PhD

Arch Dermatol. 2003;139:373-375.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Commentary on: Prophylaxis with single-dose doxycycline for the prevention of Lyme disease after an Ixodes scapularis tick bite
Nadelman RB, Nowakowski J, Fish D, Falco RC, Freeman K, McKenna D, Welch P, Marcus R, Agüero-Rosenfeld, Dennis DT, Wormser GP
N Engl J Med. 2001;345:79-84

Question: Is a single 200-mg dose of doxycycline effective for preventing Lyme disease after an Ixodes scapularis tick bite?

Design: Nadelman et al conducted a randomized, double-blind (patients and study personnel), placebo-controlled clinical trial over a period of 9.5 years (May 1987 to December 1996) to determine the effect of a single dose of doxycycline on prevention of Lyme disease after a tick bite. Some patients were included twice during this time. At baseline and at 3 weeks' and 6 weeks' follow-up, patients were interviewed and examined, and serum antibody tests were performed and blood cultures done for Borrelia burgdorferi. A . . . [Full Text of this Article]

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Department of Dermatology, Clinica Plató, Barcelona, Spain

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