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Arch Dermatol. 2003;139:531-536.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Diagnosis: Cellular neurothekeoma.

MICROSCOPIC FINDINGS AND CLINICAL COURSE

Histologic examination of the excised nodule showed a well-circumscribed, cellular, dermal nodule composed of spindled and epithelioid cells within a myxoid matrix. The cells were arranged in fascicles, with areas of plexiform compartmentalization. The epithelioid cells demonstrated bizarre cytologic atypia and pale eosinophilic cytoplasm. Rare mitoses were present. Immunohistochemical studies for S100 protein showed a very rare cell suggestive of weak positivity.

Three years after surgery there was still no evidence of recurrence.

DISCUSSION

Neurothekeomas are benign tumors of probable nerve sheath origin. They were originally described in 1969 by Harkin and Reed,¹ who used the name nerve sheath myxoma. In 1980, Gallager and Helwig² reported on a series of 53 dermal tumors that had similar features, coining the term neurothekeoma. A similar but distinctive, more cellular variant, with a less prominent myxoid component, was termed cellular neurothekeoma by Rosati et al³ in 1986. Unlike myxoid neurothekeoma, cellulular neurothekeoma . . . [Full Text of this Article]

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Arch Dermatol. 2003;139(4):531-536.
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