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Erythematous Facial Plaques in a Patient With LeukemiaQuiz Case
Glen H. Crawford, MD;
Albert Y. Chu, MD;
Matthew Halpern, BA;
William D. James, MD
University of Pennsylvania Medical Center, Philadelphia (Drs Crawford, Chu, and James), and Harvard Medical School, Boston, Mass (Mr Halpern)
Arch Dermatol. 2003;139:531-536.
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REPORT OF A CASE
A 43-year-old white man presented with fever and erythematous plaques that had developed in the right malar area and both ears 3 days after he had undergone intravenous cytarabine and idarubicin hydrochloride chemotherapy for acute myelogenous leukemia. The lesions were exquisitely painful and progressed to involve the periorbital and periauricular areas bilaterally. Similar lesions had developed on his upper back area after the first cycle of chemotherapy, 1 month earlier, but they had spontaneously resolved.
Physical examination revealed firm, deeply erythematous and purpuric plaques periorbitally, as well as tense edema and erythema of the ears (Figure 1). There were no pustules, vesicles, erosions, or ulcerations. There was no lymphadenopathy in the cervical, occipital, or preauricular areas. A complete blood cell count revealed pancytopenia (white blood cell count, 0.4 x 103/µL [reference range, . . . [Full Text of this Article]
RELATED ARTICLE
Erythematous Facial Plaques in a Patient With LeukemiaDiagnosis
Arch Dermatol. 2003;139(4):531-536.
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